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Cystic Fibrosis

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Term Paper TitleCystic Fibrosis
# of Words604
# of Pages (250 words per page double spaced)2.42

Cystic Fibrosis

Cystic Fibrosis is a genetic disease affecting approximately 30,000 children and adults in the United States.

Description

Cystic Fibrosis causes the body to produce an abnormally thick, sticky mucus, due to the faulty transport of sodium and chloride (salt) within cells lining organs such as the lungs and pancreas, to their outer surfaces. The thick CF mucus also obstructs the pancreas, preventing enzymes from reaching the intestines to help break down and digest food.

Symptoms/Characteristics

Cystic Fibrosis has a variety of symptoms. The most common are: very salty-tasting skin; persistant coughing, wheezing or pneumonia; excessive appetite but poor weight gain; and bulky stools. The sweat test is the standard diagnostic test for cystic fibrosis. This simple and painless test measures the amount of salt in the sweat. A high salt level indicates that a person has CF.

Method of Inheritance

One in 31 Americans (one is 28 Caucasians) - more than 10 million people - is an unknowing, symptomless carrier of the defective gene.

A individual must inherit a defective copy of the CF gene — one from each parent — to be have cystic fibrosis. Each time two carriers conceive a child, there is a 25 percent chance that the child will have CF; a 50 percent chance that the child will be a carrier; and a 25 percent chance that the child will be a non-carrier.

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Treatment/Research

The treatment of CF depends upon the stage of the disease and which organs are involved. One means of treatment, chest physical therapy, requires vigorous percussion (by using cupped hands) on the back and chest to dislodge the thick mucus from the lungs. Antibiotics are also used to treat lung infections

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